Biomedical systems is a research field and academic concept that applies principles of systems science, engineering, and quantitative analysis to understand biological and physiological phenomena. It investigates the complex, dynamic interactions within living organisms, spanning multiple scales from molecular networks and cellular processes to organ systems and entire populations, characterized by an interdisciplinary approach integrating computational modeling, data science, and experimental methodologies. Its significance lies in providing a comprehensive framework for analyzing health and disease, enabling the identification of emergent properties and facilitating the development of predictive models, targeted diagnostics, and novel therapeutic strategies.